M48 Ophthalmology Acupuncture: How Makari Wellness Treats Degenerative Eye Disease

When Conventional Eye Care Reaches Its Edge

The diagnosis arrives, and with it, a conversation that many patients describe as surprisingly short. Macular degeneration — watch it, protect what’s left. Retinitis pigmentosa — there’s no reversal, manage the decline. Glaucoma — medicate the pressure, monitor the nerve. Conventional ophthalmology has accomplished extraordinary things, but for the slow-burn degenerations, the honest answer is often: there is not much more we can do.

That’s where patients find us. At Makari Wellness, Michael Woodworth, M.S., L.Ac. has worked with people navigating degenerative eye conditions since 2005. The work is grounded in a specialized acupuncture microsystem called M48 — and in classical Chinese medicine’s long-standing recognition that the eye is not isolated from the constitutional terrain of the body. This post is our introduction to how we think about vision care, what the M48 protocol actually is, and what we can and cannot honestly say about its role.

The Classical Map: The Eye as a Window Into the Whole Body

In Chinese medicine, the eye is never understood in isolation. The classical teaching — 肝開竅於目 (Gān Kāi Qiào Yú Mù) — holds that the Liver opens to the eyes. Liver Blood nourishes the retina and optic nerve; Liver Qi in its free-flowing state maintains visual clarity. When Liver Blood becomes deficient, the eyes are dry and blurred. When Liver Fire ascends, the eyes redden and ache. When Liver Yang rises unchecked, pressure builds within.

But the Liver is only the most direct connection. Classical theory maps the entire eye through a framework called the Five Wheels (Wǔ Lún, 五輪), distributing eye anatomy across the five organ systems:

• Water Wheel (Shuǐ Lún, 水輪): Pupil → Kidney
• Wind Wheel (Fēng Lún, 風輪): Iris and cornea → Liver
• Blood Wheel (Xuè Lún, 血輪): Inner and outer canthi → Heart
• Flesh Wheel (Ròu Lún, 肉輪): Eyelids → Spleen
• Qi Wheel (Qì Lún, 氣輪): Sclera and conjunctiva → Lung

This framework is complemented in Makari’s clinical work by Dr. Dzung’s Five Regions map — a contemporary ophthalmology-specific lens that organizes the same anatomy by functional zone: the pupil reflects Kidney function, the iris reflects Liver, the blood vessels reflect Heart, the sclera reflects Lung, and the eyelids reflect Spleen. Together, these two frameworks give us the clinical rationale for which organ pattern is most relevant to a given eye condition — and that determines both the acupuncture protocol and the herbal formula.

What M48 Is — And Why It’s Makari’s Specialty

MA48 (Micro Acupuncture 48), developed by Andy Rosenfarb, ND, LAc, is a 48-point distal microsystem built on the ECIWO holographic principle (Embryo Contains Information of the Whole Organism) — a framework established by Professor Yingqing Zhang asserting that every segment of the body contains a complete informational map of the whole. The M48 system maps that whole-body information onto 48 specific points: 24 on the hands and 24 on the feet. All treatment is distal. No needles go near the eye itself.

What makes M48 clinically distinctive is its A/B point polarity system — each anatomical region has two point correspondences that access different layers of function:

• A points (Yang, distal): Access the functional and sensory dimension. Used for acute presentations, excess patterns, and restoring active function. In the eye, LR-A (the Liver’s functional point) is the single most-used point across virtually every condition — because Liver governs the eyes’ sensory output.
• B points (Yin, proximal): Access the structural and constitutional dimension. Used for chronic deficiency, deep atrophy, and root-level depletion. KI-B, for example, accesses the Kidney’s constitutional substrate — the Essence (Jīng, 精) that underpins retinal integrity.

In practice, M48 uses 34-gauge half-inch needles inserted at approximately 45° onto the periosteum, with a typical retention of 30 minutes (range 15–45). Response is expected within one to four treatments. About 15% of patients simply do not respond — and we say that plainly at the start of every course of care.

Four Categories of Eye Disease in the M48 Framework

The M48 system organizes all ophthalmologic presentations into four pathological categories, each with its own dominant acupuncture approach:

• Drying: Liver and Kidney Yin deficiency leading to slow structural atrophy. This is the category for dry AMD, dry eye disease, and retinitis pigmentosa — conditions defined by the progressive loss of moist, nourished tissue.
• Bleeding: Heat combined with Spleen Qi deficiency that fails to hold Blood in its vessels. Wet AMD (with its pathological new vessel growth) and diabetic retinopathy with neovascularization fall here.
• Clogging: Qi and Blood stasis obstructing the retinal collaterals. Retinal vein occlusion, traumatic injury, post-surgical complications, and diabetic hemorrhage occupy this category.
• Pressure: Liver Yang rising or Qi stagnation driving elevated intraocular pressure or optic nerve stress. Glaucoma — both elevated-pressure and normal-tension varieties — is the primary condition in this category.

In every session, a practitioner palpates for hot or tender points within the relevant category zone before needling — the reactive points guide the final selection. This is not a fixed recipe; it’s a reading of what the body’s terrain is expressing that day.

Scalp Acupuncture and the Vision Area

M48 point selection is complemented, in appropriate cases, by scalp acupuncture targeting the Occipital Vision Area (枕上視覺區) — the scalp zone mapped to the cortical visual cortex and optic nerve, located approximately 1 cm lateral to the external occipital protuberance midpoint and 4 cm superior, following the Dr. Karl Tai lineage.

What distinguishes scalp Vision Area work is mandatory electro-stimulation: Dense-Disperse wave applied to Vision Area needles using what Tai calls the “Pulling Qi Method” (Chōu Qì Fǎ, 抽气法). The galvanic current drives enhanced retinal blood flow and optic-nerve conduction — and many patients report a subjective “immediate brightening” within minutes of stimulation. This sensory response does not constitute a treatment outcome, but it is clinically meaningful as an indicator of neural engagement.

The standard scalp set is Vision Three Needles (Shì Sān Zhēn, 視三針) — three needles placed in the Occipital Vision Area in a triangular arrangement. For most conditions, this is combined with periorbital adjuncts (BL-2, SJ-23) and, where appropriate, GB-20 for its head-and-eye-benefiting action with electro at 1–4 Hz for chronic degenerations.

Chinese Herbs and Functional Medicine: The Two Supporting Layers

Acupuncture opens the channel. Herbs sustain the change between sessions. Every Makari eye patient who proceeds to a full course of care receives a classical Chinese herbal formula matched to their pattern — not a generic eye-health supplement, but a custom preparation designed for the constitutional picture we find in the intake.

The Liver-Kidney Yin deficiency pattern that underlies most dry degenerations calls for Gou Qi Zi (Gǒu Qǐ Zǐ, 枸杞子) — wolfberry, the classical “brightens the eyes” herb and the richest known food source of zeaxanthin — alongside Nu Zhen Zi (Nǚ Zhēn Zǐ, 女贞子, ligustrum) and Ju Hua (Jú Huā, 菊花, chrysanthemum), the trio that nourishes Liver-Kidney Yin and gently clears the visual field. Wet or hemorrhagic patterns add Blood-moving herbs like Dan Shen (Dān Shēn, 丹参, salvia root) and San Qi (Sān Qī, 三七, notoginseng).

Functional medicine supplements integrate at the category level: carotenoid antioxidants for macular protection, mitochondrial support for neuro-optic tissue, and microcirculatory agents for retinal and optic nerve perfusion. We approach FM through the same pattern-diagnosis lens — the intake identifies where the terrain is most compromised; the formula addresses both the classical root and the upstream functional drivers simultaneously.

What the Research Shows

A 2026 systematic review in Frontiers in Medicine by Bautista-Hernández MA and colleagues examined existing clinical studies on acupuncture for inflammation-related ocular conditions. Their honest conclusion: current evidence is insufficient to make definitive claims — studies are heterogeneous, sample sizes small, and methodology varied. This is not a verdict against acupuncture. It is a call for better, more standardized integrative research. Frontiers in Medicine, 2026.

We cite this because we think patients deserve that honesty. Integrative eye care is a serious, active area of clinical inquiry. Practitioners around the world are studying these conditions because there are plausible mechanisms — particularly around microcirculation, neuroprotection, and autonomic regulation — that deserve rigorous investigation. We work in that space with clinical care and intellectual humility, not with promises.

Curious? Let’s Talk.

If you or someone you love is navigating degenerative eye disease and wondering what integrative acupuncture and herbal support might look like, we’d love to have that conversation.

The M48 protocol isn’t a promise — it’s a conversation. One grounded in classical theory, clinical experience, and an honest engagement with the evolving science.

Makari Wellness — Michael Woodworth, M.S., L.Ac. (established 2005)
Specializing in degenerative eye disease via the M48 protocol

Call us: (888) 871-8889
Book online: makariwellness.com/book-appointment

Oceanside: 2111 S. El Camino Real, Suite 301, Oceanside, CA 92054
San Diego: 16486 Bernardo Center Drive, Suite 218, San Diego, CA 92128

This content is educational and does not constitute medical advice. Acupuncture and herbal medicine are not replacements for conventional ophthalmologic care. Always continue your care with your ophthalmologist.